HORDB

ID: hor002622
Uniprot ID: O44540
Protein name: NLP-13
Gene name: nlp-13
Organism: Caenorhabditis elegans
Family: NA
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: AEDYERQIMAF
Length: 11(123-133)
Propeptide: MQRSLQIFCIMSAIAMAYSQGSRDDNQSAKRNDFSRDIMSFGKRSGNTADLYDRRIMAFGKRQPSYDRDIMSFGKRSAPSDFSRDIMSFGKRSSSMYDRDIMSFGKRSPVDYDRPIMAFGKRAEDYERQIMAFGRRK
Signal peptide: MQRSLQIFCIMSAIAMAYS
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002622_AF2.pdb

hor002622_ESM.pdb

Mass:	155107	Formula:	C60H89N15O20S
Absent amino acids:	CGHKLNPSTVW	Common amino acids:	AE
pI:	3.93	Basic residues:	1
Polar residues:	1	Hydrophobic residues:	4
Hydrophobicity:	-63.64	Boman Index:	-2907
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	53.64
Instability Index:	4847.27	Extinction Coefficient cystines:	1490
Absorbance 280nm:	149

PubMed ID: 20013198
Title: Approaches to Identify Endogenous Peptides in the Soil Nematode Caenorhabditis elegans